PROBLEM TO BE SOLVED: To provide a pharmaceutical composition which can be dissolved well in a neutral region and contains a compound I, a pharmacologically acceptable salt or the compound, or a solvate of the compound or the pharmacologically acceptable salt as an active ingredient.SOLUTION: The present invention relates to a pharmaceutical composition comprising (A) N-(5-chloropyridine-2-yl)-N-((1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-{[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino}-cyclohexyl)ethanediamide, a pharmacologically acceptable salt of the compound, or a solvate of the compound or the pharmacologically acceptable salt, and (B) fumaric acid.SELECTED DRAWING: None【課題】本発明の課題は、中性領域における溶出が良好な、化合物Ｉ、その薬理上許容される塩又はそれらの溶媒和物を有効成分として含有する医薬組成物を提供することにある。【解決手段】(A)N1-(5-クロロピリジン-2-イル)-N2-((1S,2R,4S)-4-[(ジメチルアミノ)カルボニル]-2-{[(5-メチル-4,5,6,7-テトラヒドロチアゾロ[5,4-c]ピリジン-2-イル)カルボニル]アミノ}シクロヘキシル)エタンジアミド、その薬理上許容される塩またはそれらの溶媒和物と(B)フマル酸を含有する医薬組成物。【選択図】なし
