The present invention provides preparations of MSCs with important therapeutic potential. The MSC cells are non-primary cells with an antigen profile comprising less than about 1.25% CD45+ cells (or less than about 0.75% CD45+), at least about 95% CD105+ cells, and at least about 95% CD166+ cells. Optionally, MSCs of the present preparations are isogenic and can be expanded ex vivo and cryopreserved and thawed, yet maintain a stable and uniform phenotype. Methods are taught here of expanding these MSCs to produce a clinical scale therapeutic preparations and medical uses thereof.L'invention concerne des cellules chargées de nanoparticules et des compositions utiles pour améliorer l'imagerie et la thérapie, par exemple la radiothérapie. L'invention concerne aussi des procédés de fabrication de cellules chargées de nanoparticules, des procédés d'administration des cellules chargées de nanoparticules et des procédés de traitement et/ou d'imagerie.
