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ARTIFICIAL MATCH-TYPE MIRNA FOR CONTROLLING GENE EXPRESSION AND USE THEREFOR
专利权人:
Bonac Corporation
发明人:
KURODA, Masahiko,OHNO, Shinichiro,AOKI, Eriko,YOSHIDA, Yasuhiko,KATO, Shiori,OHGI, Tadaaki
申请号:
EP14874254
公开号:
EP3088525A4
申请日:
2014.12.27
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present invention provides a new artificial match-type miRNA utilizing miRNA. A single strand nucleic acid containing X region and Y region, wherein the 3-terminal of the X region and the 5-terminal of the Y region are linked via a linker region of a non-nucleotide structure, the X region contains a guide strand sequence of a mature miRNA, and the Y region contains a sequence completely complementary to the X region is an artificial match-type miRNA. The artificial match-type miRNA can suppress expression of the target gene.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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