The invention provides for sorghum plants and plant parts developed through tissue culture, gene editing or other methods of mutagenesis in which the plant or plant parts have increased tolerance to one or more acetyl-CoA carboxylase (ACC) herbicides at levels that would normally inhibit the growth of wild-type sorghum plants. In this context, the sorghum plant may be tolerant to any herbicide capable of inhibiting acetyl-CoA carboxylase enzyme activity. The present invention allows for the screening of ACC herbicide tolerant hybrids with markers or application of ACC inhibiting herbicides, and for the removal of unwanted vegetation with application of ACC inhibiting herbicides from seed and grain production fields.
