ActRII receptor polypeptides, methods and compositions

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专利权人:

Acceleron Pharma Inc.

发明人:

Knopf, John,Seehra, Jasbir

申请号：

AU2012244215

公开号：

AU2012244215B2

申请日:

2012.10.25

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

#$%^&*AU2012244215B220141127.pdf#####Abstract In certain aspects, the present invention provides compositions and methods for modulating (promoting or inhibiting) growth of a tissue, such as bone, cartilage, muscle, fat, and/or neuron. The present invention also provides methods of screening compounds 5 that modulate activity of an ActRII protein and/or an ActRII ligand. The compositions and methods provided herein are useful in treating diseases associated with abnormal activity of an ActRII protein and/or an ActRII ligand.

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