593894 An irradiation device (10) for insertion into an orifice of a human patient, the orifice being the female reproductive tract or the rectum and the device being for providing photodynamic therapy thereto. The device comprises: a housing (1) adapted to be fully inserted and secured in the orifice, the housing enclosing an LED lamp system (5) and a power source for powering the LED lamp system. The housing comprises a treatment surface (2a, 2b) with the LED system being arranged to, when the device is in operation, emit light from the treatment surface. The treatment surface is at least partially transparent to the light and has a size and/or shape adapted for complementary fit with a treatment area within the orifice such that, when the device is in operation, the treatment area is illuminated by the light. The device is independently operational while located within the orifice.