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arylamimoaryl-alkyl-substituted imidazolidine-2,4-diones, process for preparing them, drugs comprising these compounds, and their use
专利权人:
SANOFI-AVENTIS
发明人:
GERHARD JAEHNE,SIEGFRIED STENGELIN,MATTHIAS GOSSEL,THOMAS KLABUNDE,IRVIN WINKLER
申请号:
BRPI0715160
公开号:
BRPI0715160A2
申请日:
2007.07.25
申请国别(地区):
BR
年份:
2013
代理人:
摘要:
IMIDAZOLIDINE-2,4-DIONS REPLACED BY ARYLAMINARYL-ALKIL-, PROCESS FOR PREPARING THEM, MEDICINAL PRODUCTS UNDERSTANDING THESE COMPOUNDS, AND THEIR USE. The present invention relates to compounds of formula I, wherein the radicals R 1, R 2, A, D, E, G, L, p and R 1 to R 10 have the established definitions, and also their physiologically tolerated salts. The compounds are suitable, for example, as anti-obesity drugs and for treating cardiometabolic syndrome.IMIDAZOLIDINA-2,4-DIONAS SUBSTITUÍDAS POR ARILAMINOARIL-ALQUIL-, PROCESSO PARA PREPARÁ-LAS, MEDICAMENTOS COMPEENDENDO ESTES COMPOSTOS, E SEU USO. A presente invenção refere-se a compostos da fórmula I, em que os radicais R E R<;39>;, A, D, E, G, L, p e R1 a R1O têm as definições estabelecidas, e também a seus sais fisiologicamente tolerados. os compostos são adequados, por exemplo, como fármacos antiobesidade e para tratar síndrome cardiometabólica.
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