Constitutive expression of costimulatory ligands on adoptively transferred T lymphocytes

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专利权人:

Memorial Sloan-Kettering Cancer Center

发明人:

Stephan, Matthias,Sadelain, Michel

申请号：

AU2008233051

公开号：

AU2008233051B2

申请日:

2008.03.31

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

The present invention provides immunoresponsive cells, including T cells,cytotoxic T cells, regulatory T cells, and Natural Killer (NK) cells, expressingat least one of an antigen- recognizing receptor and a co-stimulatory ligandand methods of use therefore for the treatment of neoplasia and other pathologieswhere an increase in an antigen-specific immune response is desired.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/