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Fatty acid treatment for cardiac patients
专利权人:
Charles R. Roe
发明人:
Charles R. Roe
申请号:
US12538038
公开号:
US08507558B2
申请日:
2009.08.07
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A method of treating patients in need of treatment for a cardiac disorder has been found which comprises administering to the patient a seven carbon fatty acid compound or derivative thereof, wherein the compound or derivative thereof is able to readily enter the mitochondrion without special transport enzymes. A dietary formulation suitable for treatment of heart tissue in cardiac or surgical patients has been found which comprises a seven-carbon fatty acid chain, wherein the seven-carbon fatty acid chain is characterized by the ability to transverse the inner mitochondrial membrane by a transport mechanism which does not require carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, or carnitine/acylcarnitine translocase and the ability to undergo mitochondrial β-oxidation, and wherein the compound is selected from the group consisting of n-heptanoic acid or a derivative thereof, a triglyceride comprising n-heptanoic acid or a derivative thereof, and triheptanoin or a derivative thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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