Kevin Kwong-Hon Chow,Zhongzhen Yi,Donald R. Shaffer,Stephen M. G. Gottschalk
申请号:
US14773416
公开号:
US20160024175A1
申请日:
2014.03.10
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Embodiments of the disclosure include compositions and methods useful for treating cancers that are sensitive to a chemotherapy, such as temozolomide. The methods allow effective cell immunotherapy to be used with chemotherapy when the cell immunotherapy is susceptible to being rendered ineffective by the chemotherapy. In specific aspects, the cancer is being treated by temozolomide (TMZ) and tumor antigen-specific T-cells that are resistant to TMZ.