A method of forming and preserving a bioremodelable, biopolymer scaffoldmaterial by subjecting animal tissue, particularly fetal or neo-natal tissue,to chemical and mechanical processing. The process includes, but is notlimited to, harvesting the tissue, optionally extracting growth anddifferentiation factors from the tissue, inactivating infective agents of thetissue, mechanically expressing undesirable components from the tissue,delipidizing the tissue, washing the tissue, optionally drying the tissue andoptionally cross-linking the tissue not necessarily in the order described.The resulting product, EBM, is characterized by its microbial, fungal, viraland prion inactivated state. EBM is strong, bioremodelable, drapable and doesnot undergo calcification. EBM supplants previous inventions because of itsunique method of preparation and broad applicability in tissue reengineering.
