The invention relates to a portable clean room for filling at least one medicine container, located in the clean room with at least one active substance, wherein: the clean room is enclosed in an airtight manner by an at least partially flexible shell, the shell has at least one active substance connection region which can be opened, and a manipulation device and at least one medicine container are located in the clean room. According to the invention, the shell has at least one actuation connection region, wherein the manipulation device has at least one filling device which can be coupled to the active substance connection region for introducing at least one active substance into the at least one medicine container arranged in the clean room, and the manipulation device can be actuated by means of an actuation device via the actuation connection region of the shell, and is designed to displace the filling device—；relative to the at least one medicine container—；and/or to actuate the filling device.
