James L. Riley,Carl H. June,Bruce R. Blazar,Keli Hippen
申请号：
US14965432
公开号：
US20160151471A1
申请日:
2015.12.10
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention provides methods and compositions for converting non-Tregs into Tregs. The converted Tregs are referred to as inducible Tregs (iTregs). The iTregs are useful for preventing, suppressing, blocking inhibiting an immune response. For example the iTregs are useful for preventing rejection of a transplanted tissue in a human or other animal host, or protecting against graft vs host disease. The iTregs can also be used to treat autoimmune diseases.
