The present invention relates to the topical cosmetic use of a Polygonum bistorta extract for stimulating the expression of perlecan and/or dystroglycan, in particular in the extracellular matrix and/or in the epithelial basement membrane, especially the dermoepidermal junction. It also relates to a cosmetic care method comprising the application, to at least one concerned area of healthy skin and/or healthy mucous membrane and/or healthy scalp, of a Polygonum bistorta extract or of a cosmetic composition comprising such an extract for stimulating the expression of perlecan and of dystroglycan, in particular in the extracellular matrix and/or in the epithelial basement membrane, especially the dermoepidermal junction. It finally relates to a Polygonum bistorta extract or a dermatological composition containing a Polygonum bistorta extract and a dermatologically acceptable excipient for topical use in the treatment and/or prevention of rosacea, telangiectasias, chapping and/or disorders of the buccal and/or ocular mucous membranes.
