6-AMINO-2,4-DIHYDROPYRANO [2,3-C] PYRAZOLES AND METHODS OF USE

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专利权人:

Purdue Research Foundation

发明人:

Antonella Pepe,Andrew Mesecar

申请号：

US16493978

公开号：

US20200078336A1

申请日:

2018.03.29

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The present invention generally relates to 6-amino-2,4-dihydropyrano [2,3-c] pyrazoles as a ubiquitin specific protease 7 (USP7) inhibitor useful for the treatment of diseases mediated by malfunction of USP7, such as inflammation, cancer, and immunological disorders. The invention described herein also pertains to pharmaceutical compositions and methods for treating diseases mediated by malfunction of USP7, in mammals using compounds disclosed herein.

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