The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a Hepatitis B Virus gene. The invention also relates to a pharmaceutical composition comprising the dsRNA or nucleic acid molecules or vectors encoding the same together with a pharmaceutically acceptable carrier； methods for treating diseases caused by Hepatitis B Virus infection using said pharmaceutical composition； and methods for inhibiting the expression of a Hepatitis B Virus gene in a cell.本發明係關於一種用於抑制B型肝炎病毒基因表現之雙股核糖核酸(dsRNA)。本發明亦關於一種包含該dsRNA或編碼該dsRNA之核酸分子或載體以及醫藥學上可接受之載劑的醫藥組合物；使用該醫藥組合物治療由B型肝炎病毒感染引起之疾病之方法；及用於抑制細胞中之B型肝炎病毒基因表現之方法。
