Nucleic acid fragments that bind to the target protein

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专利权人:

タグシクス・バイオ株式会社

发明人:

平尾 一郎,平尾 路子,山重 りえ,横山 茂之

申请号：

JP2013544308

公开号：

JP6307675B2

申请日:

2012.11.15

申请国别(地区):

JP

年份:

2018

代理人:

摘要：

An object of the present invention is to develop and provide a method for efficiently producing a nucleic acid aptamer, particularly, a DNA aptamer, having higher specificity and binding activity against a target substance than those of nucleic acid aptamers obtained by conventional methods. The present invention provides a transcribable or replicable nucleic acid aptamer comprising a natural nucleotide and a non-natural nucleotide having an artificial base-pairable artificial base. The present invention also provides a method for sequencing a non-natural nucleotide-containing single-stranded nucleic acid molecule selected from a single-stranded nucleic acid library.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/