IDENTIFICATION OF A MICRO-RNA (miR-208) THAT ACTIVATES EXPRESSION OF BETA-MYOSIN HEAVY CHAIN FOR USE IN CARDIAC HYPERTROPHY CONDITIONS

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专利权人:

THE UNIVERSITY OF TEXAS SYSTEM;BOARD OF REGENTS

发明人:

OLSON, ERIC,VAN ROOIJ, EVA

申请号：

NZ57456307

公开号：

NZ574563A

申请日:

2007.07.31

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

Discloses the use of an engineered single-stranded oligonucleotide in the manufacture of a medicament for preventing or treating pathologic cardiac hypertrophy, heart failure, or myocardial infarction. The disclosed oligonucleotide is a modified small interfering RNA molecule that is complementary to a portion of gene sequence miR-208.

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