TRAITEMENT DU CANCER DU POUMON À PETITES CELLULES AVEC UN INHIBITEUR DE PARP

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专利权人:

Medivation Technologies LLC

发明人:

FENG, Ying,POST, Leonard, E.,SHEN, Yuqiao,RU, Yuanbin,WANG, Evelyn,YU, Karen

申请号：

EP16860716

公开号：

EP3368041A4

申请日:

2016.10.26

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

Described are methods of treatment of a small cell lung cancer subject expressing Schlafen-11 (SLFN 11) with a Poly (ADP-ribose) polymerases (PARP) inhibitor or a pharmaceutically acceptable salt thereof. Specifically, the method comprising detecting SLFN 11 in a tumor cell sample from the subject, and administering effective amount of a PARP inhibitor, such as talazoparib or the tosylate salt of talazoparib, to the subject.

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