PROCESS FOR THE MANUFACTURE OF A PHARMACEUTICAL PRODUCT COMPRISING CITRIC ACID, MAGNESIUM OXIDE, POTASSIUM BICARBONATE AND SODIUM PICOSULFATE, PHARMACEUTICAL COMPOSITION COMPRISING GRANULES OBTAINED BY SUCH PROCESS AND INTERMEDIATE
Compositions are provided that are useful for the preparation of a medicament. The compositions comprise granules having a layer of sodium picosulphate coated on potassium bicarbonate. Additional granules having a layer of magnesium oxide coated on a core of citric acid are also provided. The two types of granules may be combined to obtain mixtures (preferably homogeneous or substantially homogeneous mixtures) of the two types of granules, which are useful, e.g., as pharmaceutical compositions.구연산, 산화 마그네슘, 중탄산칼륨 및 피코황산나트륨, 및 선택적으로, 사카린 나트륨 및/또는 오렌지 향료의 균질한 또는 실질적으로 균질한 혼합물을 포함하는, 약제학적 조성물의 제조 방법； 생성물, 중간 생성물 및 그의 용도.
