Ethan Dmitrovsky,Bret C. Hassel,Sutisak Kitareewan,Ian Pitha-Rowe
申请号:
US13621377
公开号:
US20130041016A1
申请日:
2012.09.17
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Compositions and methods of using compositions that induce UBE1L or a ubiquitin-like protein ISG15, or inhibit a deconjugase UBP43 to degrade oncogenic proteins and enhance apoptosis of cancer (neoplastic) or pre-cancerous (pre-neoplastic) cells are provided. Methods for the prevention or treatment of cancer via administration of these compositions are also provided.