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METHOD FOR PREDICTION OF ESSENTIAL ARTERIAL HYPERTENSION DEVELOPMENT IN CHILDHOOD
专利权人:
Federalnoe gosudarstvennoe byudzhetnoe obrazovatelnoe uchrezhdenie vysshego obrazovaniya "Uralskij gosudarstvennyj meditsinskij universitet" Ministerstva zdravookhraneniya Rossijskoj Federatsii (FGBOU
发明人:
Samarina Olga Vyacheslavovna (RU),Самарина Ольга Вячеславовна (RU),Kovtun Olga Petrovna (RU),Ковтун Ольга Петровна (RU),Averyanov Oleg Yurevich (RU),Аверьянов Олег Юрьевич (RU),Chujkov Aleksandr Yurev,Чуйков Александр Юрьеви
申请号:
RU2017103036
公开号:
RU0002641378C1
申请日:
2017.01.30
申请国别(地区):
RU
年份:
2018
代理人:
摘要:
FIELD: medicine.SUBSTANCE: method includes identification of risk factors, namely: X1-overweight, this indication shall be 1, and the absence of indication is 0; X2 is the total of identified risk factors; X3 is burdened heredity of hypertension, the presence of this indication shall be 1, and the absence is 0; X4 is bearing of 894 NOS3 gene t-allele, the presence of this indication shall be 1, and the lack of sign-0; X5 is pregnancy pathology, the presence of this indication shall be 1, and the absence is 0; X6 is perinatal lesion of the central nervous system (CNS PL) in history, the presence of this indication shall be 1, and the absence is 0; X7 is adverse material conditions of family existence, the presence of this indication shall be 1, and the absence is 0; X8 is low weight at birth, the presence of this indication shall be 1, and the absence is 0; X9 is single-parent family, the presence of this indication shall be 1, and the absence is 0; X10 child smoking, the presence of this indication shall be 1, and the absence is 0; X11 is secondhand smoking (smoking parents), the presence of this indication shall be 1, and the absence is 0; X12 is bearing of 1166 AGTR1 gene C-allele, the presence of this indication shall be 1, and the absence is 0; X13 is combined bearing of CYP11B2 + GNB3 genes polymorphisms, the presence of this indication shall be 1, and the absence is 0; X14 is bearing of 344 gene CYP11B2 T-allele, the presence of this indication shall be 1, and the absence is 0; X15 is bearing of 825 GNB3 gene T-allele, the presence of this indication shall be 1, and the absence is 0; X16 is day regimen violation, the presence of this indication shall be 1, and the absence is 0; X17 is anxious type of child's personality, the presence of this indication shall be 1, and the absence is 0; and classification functions F(1) and F(2) are calculated by the formulas: F(1)=5.99×X1+0.56×X2+15.94×X3+1.90×X4+7.96×X5+4.96×X6+7.21×X+5.91×X8+1.33×X9+4.28×X10-1.24×X11+2.33×X1
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