Jason Teckoe,Bradley J. Prusak,Jeffrey R. Gimbel,Daniel To
申请号:
US14597025
公开号:
US20150202160A1
申请日:
2015.01.14
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention is directed to immediate release film coating compositions for use on oral dosage forms such as compressed tablets and other orally-ingestible substrates which contain medium chain glycerides as detackifiers. The film coating compositions can be applied either directly to a substrate or after the substrate has been coated with a subcoat. In preferred aspects, the polymer is polyvinyl alcohol and the medium chain glycerides are mixtures of caprylic (8 carbon chain) and capric (10 carbon chain) mono- and diesters of glycerin. Aqueous suspensions comprising the inventive film coating compositions, methods of applying the coatings to substrates and the coated substrates themselves are also disclosed.