Transfemoral or temporary trans-saphenous venous endoprosthesis (100) for total vascular exclusion of the liver (120), for use in most critical surgical interventions such as, for example, in major hepatectomy and in liver trauma with relevant venous damage, comprising: - an intravenous catheter (101), with a millimeter scale, in the form of a longitudinally extended cylinder, which is flexible in order to be inserted from the femoral vein (114) or the saphenous vein directed towards the vein ( 102) lower cava; the intravenous catheter (101) has a diameter of the order of the inside diameter of the same femoral vein (114) or saphenous vein; - a cylindrical element (103) placed in the distal part of said intravenous catheter (101); the lower side of the cylindrical element (103) in the part close to said catheter (101) is oblique and has a rounded edge; - a radial expansion mechanism of said cylindrical element (103) activated under the control of a specific control device, so that, under the control of a surgeon, the intravenous catheter (101) is first installed by insertion from the Femoral vein (114) or the saphenous vein directed towards the vena cava, with the cylindrical element (103) placed in the vena cava stretch of the upper hepatic veins, and then said radial expansion mechanism of said element (103) is activated. cylindrical so that the side walls join and close the holes that connect the upper hepatic veins (113) with the inferior vein (102), allowing blood to flow into the same cylindrical element (103) while preventing a return of blood to the liver (120); in such a way, with a simultaneous Pringle maneuver that stops the blood that goes to the liver (120), a total vascular exclusion of the liver (120) is achieved, in which: - said intravenous catheter comprises a cylindrical element (132) hole; - said cylindrical element (103) is composed of a layer of flexible material (131), preferably flat and having a triangular or square shape, connected to and w