PULSE MEDICAL IMAGING TECHNOLOGY (SHANGHAI) CO.; LTD
发明人:
Shengxian TU,Miao CHU,Bing LIU,Yazhu CHEN
申请号:
US15777817
公开号:
US20180344173A1
申请日:
2016.11.04
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A method for computing fractional flow reserve (FFR), comprising: receiving geometrical parameters of a blood vessel segment comprising a proximal end and a distal end, the geometrical parameters comprising a first geometrical parameter, a second geometrical parameter and a third geometrical parameter; and with the proximal end as a reference point, deriving a reference lumen diameter function and a geometrical parameter difference function based on the geometrical parameters and the distance from the position along the segment of blood vessel to the reference point. Derivatives of the geometrical parameter difference function are calculated in multiple scales. A maximum mean blood flow velocity of the segment is obtained, and FFR is computed as a ratio of a second blood flow pressure at the first location of the blood vessel to a first blood flow pressure at the proximal end of the segment based on the multiple scales of derivative difference functions and the maximum mean blood flow velocity. The innovation of the present invention lies in the fact that the multiple scales method realizes accurate calculation of the pressure deviation within the blood vessel segment where different severity degrees of lesions coexist.