PROBLEM TO BE SOLVED: To provide a protein adhesion preventive agent capable of imparting excellent biocompatibility to the surface of an article such as a medical device, a coating liquid, and an article excellent in biocompatibility. A fluoropolymer (A) having a biocompatible group, a fluorine atom content QF of 5 to 60% by mass, and a glass transition temperature of −100 to 100 ° C., and a non-fluorinated thermosetting resin At least one non-fluorinated compound (B) selected from the group consisting of a non-fluorinated thermoplastic resin, a non-fluorinated photocurable resin and a non-fluorinated curable monomer having a polymerizable unsaturated group； A protein adhesion inhibitor comprising: a content of the fluoropolymer in the composition of 0.01 to 5% by mass.医療用デバイス等の物品の表面に優れた生体適合性を付与できるタンパク質付着防止剤、塗布液および生体適合性に優れる物品の提供。 生体親和性基を有し、フッ素原子含有率ＱＦが５～６０質量％であり、かつガラス転移温度が－１００～１００℃である含フッ素重合体（Ａ）と、非フッ素系熱硬化性樹脂、非フッ素系熱可塑性樹脂、非フッ素系光硬化性樹脂および重合性不飽和基を有する非フッ素系硬化性単量体からなる群から選ばれる少なくとも１種の非フッ素系化合物（Ｂ）と、を含むタンパク質付着防止剤であって、前記組成物中の前記含フッ素重合体の含有量が０．０１～５質量％である、タンパク質付着防止剤。
