abstract the invention provides combinations comprising gdc-0068 or gdc-0941, or a pharmaceutically acceptable salt thereof and mehd7945a. The combinations are particularly useful for treating hyperproliferative disorders, such as cancer (e.g., triple negative breast cancer). "combinations of a pi3k / akt inhibitory compound with a her3 / egfr inhibitory compound and methods of use" the invention provides combinations comprising gdc-0068 or gdc-0941, or a pharmaceutically acceptable salt thereof and the same. -hd7945a. The combinations are particularly useful for treating hyperproliferative disorders such as cancer (eg triple negative breast cancer).abstract the invention provides combinations comprising gdc-0068 or gdc-0941, or a pharmaceutically acceptable salt thereof and mehd7945a. the combinations are particularly useful for treating hyperproliferative disorders, such as cancer (e.g., triple negative breast cancer). tradução do resumo resumo "combinações de um composto inibidor de pi3k/akt com um composto inibidor de her3/egfr e métodos de uso" a invenção provê combinações que compreendem gdc-0068 ou gdc-0941, ou um sal farmaceuticamente aceitável do mesmo e me-hd7945a. as combinações são particularmente úteis para tratar distúrbios hiperproliferativos, tal como câncer (por exemplo, câncer de mama triplo negativo).
