Maria Teresa Di Martino;Pierfrancesco Tassone;Pierosandro Tagliaferri
发明人:
Pierfrancesco Tassone,Pierosandro Tagliaferri,Maria Teresa Di Martino
申请号：
US14798660
公开号：
US09404111B2
申请日:
2015.07.14
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Inhibitors of miRNAs 221 and 222, and their use as medicaments in the treatment of multiple myeloma. The inhibitors inhibit miRNAs 221 and 222 of the type of LNA-miRNAs and have the formula +C*A*G*+A*+C*A*+A*T*+G*T*+A*+G*C, and formula C*+A*+G*+A*T*+G*T*+A*+G*C wherein letters with symbol “+” indicate the positions of LNA and symbol “*” indicates phosphorothioate bonds.
