Jan GRIMM;Fabian WIRTH;Tobias WELT;NEURIMMUNE HOLDING AG;UNIVERSITY OF ZURICH;Fabrice HEITZ
发明人:
Jan GRIMM,Fabrice HEITZ,Fabian WIRTH,Tobias WELT
申请号:
IL24773716
公开号:
IL247737D0
申请日:
2016.09.11
申请国别(地区):
IL
年份:
2016
代理人:
摘要:
Described are molecules specifically binding to human islet amyloid polypeptide (hIAPP) also known as amylin, particularly human-derived antibodies as well as fragments, derivatives and variants thereof for antagonizing islet amyloid polypeptide (IAPP) induced β-cell damage and impaired glucose tolerance winch are symptoms typically associated with diabetes mellitus type 2 (T2D).