Bruce H. KenKnight,Jeffrey L. Ardell,Imad Libbus,Badri Amurthur
申请号:
US15230023
公开号:
US20160339252A1
申请日:
2016.08.05
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Systems and methods are provided for delivering neurostimulation therapies to patients for treating chronic heart failure. A neural fulcrum zone is identified and ongoing neurostimulation therapy is delivered within the neural fulcrum zone. This neural fulcrum zone corresponds to a combination of stimulation parameters at which autonomic engagement is achieved, while the tachycardia-inducing stimulation effects are offset by the bradycardia-inducing effects, thereby minimizing side effects such as significant heart rate changes while providing a therapeutic level of stimulation.