Palbociclib and 6- (2,4-dichlorophenyl) -5- [4-[(3S) -1- (3-fluoropropyl) pyrrolidine-3-yl] oxyphenyl] -8,9-dihydro-7H-benzo [ 7] Combinations containing annulene-2-carboxylic acid and their use for the treatment of cancer
Palbociclib and 6- (2,4-dichlorophenyl) -5- [4-[(3S) -1- (3-fluoropropyl) pyrrolidine-3-yl] oxyphenyl] -8,9-dihydro-7H-benzo [ 7] Combinations with annulene-2-carboxylic acid or pharmaceutically acceptable salts thereof, pharmaceutical compositions containing such combinations, and their therapeutic use, especially for the treatment of cancer, including breast cancer. Therapeutic use is provided herein.パルボシクリブと6-(2,4-ジクロロフェニル)-5-[4-[(3S)-1-(3-フルオロプロピル)ピロリジン-3-イル]オキシフェニル]-8,9-ジヒドロ-7H-ベンゾ[7]アヌレン-2-カルボン酸又はその薬学的に許容しうる塩との組み合わせ、このような組み合わせを含有する医薬組成物、及びその治療上の使用、特に乳癌を含む癌の処置のためのその治療上の使用が本明細書において提供される。