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5-dimethylamine-3-(1-[2S-hydroxi-3-[5-sulfur-3-(trifluorophenyl) -4,5,6,7-tetrahydropyrazole [4,3-C] pyridine-1-il] propil) -1-methyl-1,3-di-imidazo [4,5-b] pyridine-2-ona； crystalline salt-hexachlorobenzene； a compound intermediate preparation He's very useful for autoimmune disorders.
- 专利权人:
- JANSSEN PHARMACEUTICA N.V.
- 发明人:
- LIANG JIMMY T. MANI NEELAKANDHA S.
- 申请号：
- CL2012000353
- 公开号：
- CL2012000353A1
- 申请日:
- 2012.02.10
- 申请国别(地区):
- CL
- 年份:
- 2013
- 代理人:
- 摘要：
- Process for the preparation of compounds derived from arilpirazol - 3 - 1 - propanol piperidin； a Crystalline Salt of 5 - 3 - (dimethylamino) - 1 - (2 - hydroxy - 3 - [5 - (4 - metanosulfonil - 3 - trifluoromethyl phenyl) - 4,5,6,7 - tetrahydro - 4.3 - pyrazolo [c] pyridin-1-yl}] propyl - piperidin-4-yl) Il - 1 - methyl 1,3 Dihydro imidazo [4,5-b] pyridin - 2 - ona, useful in Transplant rejection.Proceso de preparación de compuestos derivados de 1-arilpirazol-3-piperidin-propanol； una sal cristalina de 5-dimetilamino-3-(1-{2s-hidroxi-3-[5-metanosulfonil-3-(4-trifluorometil-fenil)-4,5,6,7-tetrahidro-pirazolo[4,3-c]piridin-1-il]propil}-piperidin-4-il)-1-metil-1,3-dihidro-imidazo[4,5-b]piridin-2-ona, útil en rechazo a trasplantes.
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
