SUBSTANCES AND PHARMACEUTICAL COMPOSITIONS FOR THE INHIBITION OF GLYOXALASES AND THEIR USE AGAINST BACTERIA

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专利权人:

发明人:

申请号：

EP06724347.7

公开号：

EP1877141B1

申请日:

2006.04.13

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

The present invention pertains to substances of the formula (I) wherein X is O or S and R1-R4 are defined in the claims as inhibitors of glyoxalase I and/or II, pharmaceutical compositions comprising one or more compounds according to formula (I) and the use of one or more compounds according to formula (I) for the treatment of diseases associated with increased glycolytic metabolism. In one embodiment, the disease is a bacterial infection.

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