587108 RECOMBINANT INFLUENZA VIRUS-LIKE PARTICLES (VLPS) PRODUCED IN TRANSGENIC PLANTS EXPRESSING HEMAGGLUTININ Provided is a nucleic acid comprising a nucleotide sequence encoding an influenza hemagglutinin (HA) wherein the nucleotide sequence comprises a regulatory element that is operative in a plant, the regulatory element comprising a Cowpea Mosaic Virus (CPMV) regulatory region. The DNA constructs can be used to express the antigen in plants to produce an antibody or a plant extract for inducing immunity to influenza virus.
