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Method of preserving a platelet concentrate under elevated xenon concentration and pressure with refrigeration
专利权人:
Ilya Y. Ilyin
发明人:
Ilya Y. Ilyin,Maria G. Tkachman,Maria E. Urusova,James S. Jones,William E. Grieshober,Semyon Kogan,Pavel Butylin,Rostislav Khorenyan
申请号:
US12498857
公开号:
US08158339B2
申请日:
2009.07.07
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Provides are improved methods for storing platelets and compositions that contain stored platelets for use in transfusions. The method entails obtaining a platelet concentrate from blood obtained from an individual and holding the platelet concentrate in at refrigerated temperatures under an atmosphere having a pressure of from 3.5 to 5 bars comprising more than 65% xenon and for at least one week. Also provided is a refrigerated composition that contains a platelet concentrate, wherein the platelet concentrate contains xenon, and wherein the platelet concentrate has been isolated from an individual for at least seven days.
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