A drug packaging device in which both sheets are easily connectable to each other with a simple construction is provided. A working plate 151 having a first portion AR1 for temporarily fixing an end portion of a sheet remaining at a drug filling unit side, and a second portion AR2 for temporarily fixing an end portion of a new sheet is provided. The end portions of the respective packaging sheets which are temporarily fixed at the first portion AR1 and the second portion AR2 are connectable to each other.
