Icahn School of Medicine at Mount Sinai;Yeda Research and Development Co. Ltd. At the Weizmann Institute of Science
发明人:
SCHUCHMAN, EDWARD H.,GULBINS, ERICH,FUTERMAN, ANTHONY,PEWZNER-JUNG, YAEL
申请号：
PL13797635
公开号：
PL2854910T3
申请日:
2013.05.31
申请国别(地区):
PL
年份:
2020
代理人:
摘要：
The present invention relates to a method for treating or preventing pathogenic infections in a subject having Cystic Fibrosis, COPD, and/or an open wound. This method involves selecting a subject having Cystic Fibrosis, COPD, and/or an open wound and administering to the selected subject a ceramidase under conditions effective to reduce ceramide and to treat or prevent the pathogenic infection. Th e method also involves the use of a ceramidase in combination with other drugs to reduce infection, reduce ceramide, or improve lung function in Cystic Fibrosis, COPD, and/or open wound patients.
