PFIZER INC;SQUIBB BRISTOL MYERS CO;BRISTOL-MYERS SQUIBB COMPANY
发明人:
RICHARD G. NAUSE,NAUSE RICHARD G
申请号:
BRPI1010739
公开号:
BRPI1010739A2
申请日:
2010.06.15
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
The present invention provides a process for producing a solid amorphous dispersion of apixaban comprising dissolving apixaban and one or more polymers in a solvent, which dissolves both apixaban and the one or more polymers and removing the solvent by spray drying; a solid amorphous dispersion prepared according to the process; as well as a dosage form comprising the solid amorphous dispersion.