The invention describes methods and agents for improving cosmetic appearance,forpromoting, improving or restoring health of cells and tissues, preferablyskin, andmore preferably, for restoring aged or damaged skin to a healthy appearance.Thisinvention relates to the use of cells and cellular extracts in rejuvenationand healingtechnologies thereby improving healing and regeneration of all bodily tissuesandorgans. The invention also relates to prevention of deterioration, damage andmalfunction of cells and tissues, and to promote, improve or exceed cellularfunctionin order to promote, improve and exceed appearance, vitality and health. Insomeembodiments, the invention relates to compositions of cells, eggs, cellextracts, eggextracts, and extract components such as purified nucleic acids, polypeptides,lipids,carbohydrates or other natural products.