Tannishtha Reya,Hyog Y. Kwon,Takahiro Ito,Dong-Wook Kim,Vivian Oehler,Jerald Radich
申请号:
US13320324
公开号:
US09173963B2
申请日:
2010.05.14
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Disclosed are methods of predicting responsiveness of a cancer cell to a tyrosine kinase inhibitor, and methods of predicting the risk of progression of a cancer cell to a more aggressive form. Also provided are methods of reducing proliferation or promoting differentiation of a cancer cell having reduced level of Numb or increased level of Msi. Further disclosed are methods of treating a mammalian subject having cancer and methods of assessing an agent for chemotherapeutic potential.