KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES
发明人:
LEE, KEE HOKR,이기호,SHIN, HYUN JINKR,신현진,JUNG, WON HEEKR,정원희,SONG, JIE YOUNGKR,송지영,LEE, EUN JUKR,이은주,HAM, YONG HOKR,함용호,KIM, SUNG SUBKR,김성섭,HONG, SUNG HEEKR,홍성희
申请号：
KR1020160105067
公开号：
KR1020170022924A
申请日:
2016.08.18
申请国别(地区):
KR
年份:
2017
代理人:
摘要：
A clustered mitochondrial homolog (CLUH) or a BMP binding endothelial regulator (BMPER) according to the present invention is involved in differentiation into adipocytes and fat accumulation. Thus, by inhibiting the CLUH or the BMPER, the differentiation into adipocytes can be inhibited and obesity can be treated or prevented. Also, by measuring the level of expression of the CLUH or the BMPER, obesity can be diagnosed and screening an obesity treating agent or a control agent for the differentiation into adipocytes is enabled.COPYRIGHT KIPO 2017본 발명의 CLUH (Clustered mitochondrial homolog) 또는 BMPER (BMP binding endothelial regulatr)은 지방세포로의 분화 및 지방 축적에 관여하므로, 이를 억제하여 지방 세포로의 분화를 억제할 수 있으며, 비만을 치료 또는 예방할 수 있다. 또한, 상기 CLUH 또는 BMPER의 발현 수준을 측정하여 비만을 진단하고, 비만 치료제, 및 지방세포로의 분화 조절제를 스크리닝할 수 있다.
