Nobuaki TAKAHASHI,Ryosuke NAKANO,Sayaka MAEDA,Yuji ITO
申请号：
US16473482
公开号：
US20190352397A1
申请日:
2017.12.25
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The invention relates to an antibody which binds to myelin oligodendrocyte glycoprotein (MOG), an antibody fragment thereof, a hybridoma which produces the antibody or the antibody fragment, a nucleic acid containing a nucleotide sequence which encodes the antibody or the antibody fragment, a transformant cell containing a vector containing the nucleic acid, a method for producing the antibody or the antibody fragment, a composition containing the antibody or the antibody fragment and a method for detecting or measuring an antigen that is present in the brain, a method for diagnosing or treating a brain disease, a method for improving the property of an antibody of accumulating in the brain and a method for increasing the amount of an antibody in the brain which use the antibody or the antibody fragment.
