經取代之聯伸二苯化合物及其治療病毒疾病之用途农业专利-农业学术服务平台

发明人:: KOZLOWSKI, JOSEPH A.,克斯洛斯基　乔瑟夫Ａ,克斯洛斯基　喬瑟夫Ａ,SHANKAR, BANDARPALLE B.,夏卡尔　班达帕尔Ｂ,夏卡爾　班達帕爾Ｂ,克斯洛斯基乔瑟夫A,克斯洛斯基喬瑟夫A,夏卡尔班达帕尔B,夏卡爾班達帕爾B

摘要：: The present invention relates to novel Substituted Biphenylene Compounds of Formula (I):and pharmaceutically acceptable salts thereof, wherein Y1, Y2, R1, R2, R4, Ra and Rb are as defined herein. The present invention also relates to compositions comprising at least one Substituted Biphenylene Compound, and methods of using the Substituted Biphenylene Compounds for treating or preventing HCV infection in a patient.本發明係關於新穎的式(I)之經取代聯伸二苯化合物：及其醫藥學上可接受之鹽，其中Y1、Y2、R1、R2、R4、Ra及Rb係如本文所定義。本發明亦係關於包含至少一種經取代之聯伸二苯化合物的組合物，及使用該等經取代之聯伸二苯化合物治療或預防患者之HCV感染的方法。