The invention relates to a mixing device for producing a multi-component mixture, in particular for medical applications, comprising at least one first component and one second component 16, whereby the first component is a fluid mass, in particular a pasty mass, whereby the mixing device comprises a housing 2 having at least one first opening 4 and a hollow body 12, whereby the hollow body 12 comprises an internal space that contains the second component 16, and the mixing device comprises a feed plunger 20 for expelling the second component 16 from the internal space of the hollow body 12, whereby the hollow body 12 comprises a thread 18 and the feed plunger 20 comprises a counter-thread 22 that engages the thread 18 of the hollow body 12, and the mixing device comprises a propulsion element 24 that is arranged inside the housing 2, whereby the propulsion element 24 converts a flow of the first component through the housing 2 into a rotary motion, whereby the rotary motion of the propulsion element 24 screws the feed plunger 20 into the internal space of the hollow body 12, and whereby the second component 16 can thus be extruded from the hollow space into the fluid flow of the first component. The invention also relates to a cartridge system having a mixing device of this type and to an applicator having a cartridge system of this type. And lastly, the invention also relates to a method for producing a multi-component mixture, in particular using a mixing device of this type, in which a first component is being pressed into a housing 2 and generates a fluid flow therein, whereby the fluid flow drives a propulsion element 24 and makes it rotate, and whereby the rotating propulsion element 24 screws a feed plunger 20 into an internal space of a hollow body 12, whereby a second component 16 is thus extruded from the inside of the hollow body 12 into the fluid flow of the first component and mixes with the first component therein and the mixture is being extruded fro