Viral vectors encoding apoptosis-inducing proteins and methods for making and using the same

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专利权人:

Donald Bellgrau

发明人:

Donald Bellgrau,Richard C. Duke,Jerome B. Schaack

申请号：

US10825282

公开号：

US08715645B2

申请日:

2004.04.14

申请国别(地区):

US

年份:

2014

代理人:

摘要：

This invention discloses a novel method for propagation of viral vectors encoding proteins that induce apoptosis. The invention also discloses viral vectors produced by such methods and cells transfected with such vectors. Also disclosed are methods for suppressing T-lymphocyte-mediated graft rejection, for suppressing T-lymphocyte-mediated disease and for inducing apoptosis in cancer cells.

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