Yingchun Guan,Libin Lu,Jiaru Zhang,Zhen Zhang,Huaming Wang
申请号:
US16577104
公开号:
US20200009687A1
申请日:
2019.09.20
申请国别(地区):
US
年份:
2020
代理人:
摘要:
A method of preparing antimicrobial surface on medical devices: first, producing multi-functional surface with bacterial anti-adhesion and self-cleaning functions through single-stop ultrafast laser fabrication approach for development of micro/nano patterns, then producing bactericidal thin film through depositing metal nanoparticles on those micro/nano patterned surfaces. The combination of bacterial anti-adhesion and bactericidal film can inhibit initial bacterial adhesion and release heavy metal ions to kill the bacteria simultaneously. Meanwhile, the multi-functional surface with self-cleaning function can prevent the killed bacteria from accumulating at the substrate surface, thereby obtaining long-lasting antibacterial effect.