This application provides a dynamic color filter (CF) macroscopic inspection system and method. The dynamic CF macroscopic inspection system includes: a color film coating unit, configured to coat color filters on a CF glass substrate; a color film developing unit, configured to develop the CF glass substrate; a color film baking unit, configured to bake the CF glass substrate; a color film macroscopic inspection unit, configured to inspect a visual macroscopic abnormality of the CF glass substrate; a color film colorimeter unit, configured to perform a chrominance detection on the CF glass substrate; and at least one conveyor belt, including a first conveyor belt and a second conveyor belt, connected between the color film coating unit, the color film developing unit, the color film baking unit, the color film macroscopic inspection unit, and the color film colorimeter unit, and configured to transport the CF glass substrate.