PURPOSE: A composition for treating or preventing blood vessel diseases containing joiner extracts is provided to prevent activity of arginase and to increase produce of NO in blood vessel cells and main arteries. CONSTITUTION: A composition for treating or preventing blood vessel diseases contains fractions as main component. The fractions are obtained by the following steps: extracting the joiner by using alcohol； and extracting the crude extract by using ethyl acetate. The blood vessel disease is arteriosclerosis, hypertension, coronary artery disease, cerebrovascular disease, peripheral vascular disease or main artery disease. A health supplement for preventing and improving the blood vessel diseases includes fractions as main component. The fractions are obtained by the following steps: extracting the joiner by using alcohol； and extracting the crude extract by using ethyl acetate.본 발명은 소목(Caesalpiniasappan lignum)의 에틸아세테이트 분획물을 함유하는 혈관질환의 예방 및 치료용 조성물에 관한 것으로, 상기 소목의 에틸아세테이트 분획물의 처리를 통해, 아르기나아제의 활성이 억제되고, 혈관세포 및 대동맥에서의 NO의 생성이 증가하였으며, 상기 조성물은 고혈압, 동맥경화, 관상동맥질환, 뇌혈관질환, 말초혈관질환 또는 대동맥질환 등의 혈관질환을 치료할 수 있다.
