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2-ACYLAMIDOMETHYL AND SULFONYLAMIDOMETHYL BENZOXAZINE CARBAMATES FOR INHIBITION OF RORgamma ACTIVITY AND THE TREATMENT OF DISEASE
专利权人:
发明人:
Thomas D. Aicher,Chad A. VanHuis,John MacLean,Brian M. Andresen,Kenneth J. Barr,Corey Bienstock,Neville J. Anthony,Matthew Daniels,Yuan Liu,Catherine White,Blair T. Lapointe,Nunzio Sciammetta,Vladimir
申请号:
US15103407
公开号:
US20160304505A1
申请日:
2014.12.19
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention provides certain benzoxazine compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, Ra, Rb, Rc, Rd, Rg, and Cy are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds of the Formula (I) or pharmaceutically acceptable salts thereof, and methods of using the compounds of the Formula (I) or pharmaceutically acceptable salts thereof or pharmaceutical compositions comprising the same for treating diseases or conditions mediated by RORgammaT.
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