ДЕССЕР Лючия (AT),ЛОТЦ Бернхард (AT),МОР Томас (AT)
申请号：
RU2010127336/15
公开号：
RU2010127336A
申请日:
2008.12.03
申请国别(地区):
RU
年份:
2012
代理人:
摘要：
1. The use of at least one protease for the manufacture of a medicament for the treatment and / or prevention of benign prostate hypertrophy / hyperplasia, wherein the medicament is suitable for parenteral administration, wherein at least one protease is selected from the group consisting of plant proteases and microorganisms, and it is administered in an amount of from 1 to 100 mg / kg body weight. ! 2. The use according to claim 1, in which the plant protease is selected from the group consisting of bromelin, papain, ficin, ananine, balance, caricain, faustasain, hieronymim, karatazin, macrodontain, penguin, cumumisin, actinidia. ! 3. The use according to claim 1, in which the protease of the microorganisms is selected from the group consisting of nattokinase, brinase, cyprosis, spherical, subtilisin and mutanase. !4. The use according to claim 1, wherein the protease from non-mammalian animals is selected from the group consisting of krilenzyme, batroxobin, lumbrokinase, alfimerase and mutanase. ! 5. The use according to claim 1, in which at least one protease is contained in the drug in an amount of from 5 to 100% wt./weight., Preferably from 20 to 80% wt./weight., More preferably from 30 up to 70% w / w. ! 6. The use according to claim 1, wherein at least one protease is administered to an individual in an amount of from 2 to 50 mg / kg, preferably from 5 to 20 mg / kg of body weight. ! 7. The use according to claim 1, wherein the drug further comprises at least one pharmaceutically acceptable carrier, diluent and / or excipient, preferably a binding agent, excipient, disintegrant, lubricant, preservative and / or coating. ! 8. The use according to claim 1, for which1. Применение, по меньшей мере, одной протеазы для производства лекарственного средства для лечения и/или профилактики гипертрофии/гиперплазии доброкачественной простаты, где лекарственное средство подходит для парентерального введения, причем, по меньшей мере, одну протеазу выбирают из группы, сост
